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Creators/Authors contains: "Cruaud, Corinne"

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  1. ; ; ; ; ; ; ; ; ; ; et al (, Science)
    In many species with sex chromosomes, the Y is a tiny chromosome. However, the dioecious plantSilene latifoliahas a giant ~550-megabase Y chromosome, which has remained unsequenced so far. We used a long- and short-read hybrid approach to obtain a high-quality male genome. Comparative analysis of the sex chromosomes with their homologs in outgroups showed that the Y is highly rearranged and degenerated. Recombination suppression between X and Y extended in several steps and triggered a massive accumulation of repeats on the Y as well as in the nonrecombining pericentromeric region of the X, leading to giant sex chromosomes. Using sex phenotype mutants, we identified candidate sex-determining genes on the Y in locations consistent with their favoring recombination suppression events 11 and 5 million years ago. 
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    Free, publicly-accessible full text available February 7, 2026
  2. ; ; ; ; ; ; ; ; ; ; et al (, Cell)
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  3. ; ; ; ; ; ; ; ; ; ; et al (, Cell)
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